Industrial Cell Culture Technology

Content & Learning Objective

Across the spectrum from cell culture flasks to large-scale production, a variety of bioreactor types (including continuous stirred tank reactors, single-use bags, packed bed reactors and hollow fiber reactors) can be used to obtain steadily larger quantities of animal or human cells or their products (such as antibodies). The sheer number and complexity of the available types can be quite daunting when trying to understand bioreactor technology. This theoretical course provides you with basic knowledge for choosing and using bioreactors for cell cultures. Basic bioreactor functions are explained with the aid of virtual simulations.

The following topics are covered:

  • Requirements for culturing animal and human cells
  • Overview of bioreactor technologies for cell culture
  • Design, instrumentation and operation of a laboratory bioreactor

Process type (batch, fed batch, continuous)

Target Group

Technical and scientific workers with sound basic knowledge of cell culture and cell biology. Knowledge of bioreactor technology is not required.


Prof. Dr.-Ing. Ralf Pörtner studied chemical technology at Dortmund University, doing his doctorate in the Department of Mechanical and Process Engineering. After pursuing postdoctoral studies at the University of Tsukuba in Japan, he returned to Germany to take the roles of Head Engineer and Head of the Cell Culture Technology and Tissue Engineering working group at the Hamburg University of Technology. After achieving the highest German merit-based academic qualification, Habilitation, Dr. Pörtner was granted Privatdozent status, thus licensing him to teach at the university level. Since 2010 he has been an honorary professor at the Mittelhessen University of Applied Sciences in Giessen. Dr. Pörtner is currently one of the coordinators of the regeneration, implants and medical technology research department in Hamburg and also serves on the board of the Forschungszentrum Medizintechnik (FMTHH). His research focuses include developing bioreactors, especially for cell culture and microbial reactions, model-assisted control and regulation approaches, and tissue engineering.